Storage:
active substances: ethyl ether of a-bromosovaleric acid, phenobarbital, mint oil, hop oil;
1 ml of solution (26 drops) contains: ethyl ether of a-bromosovaleric acid in a 100% substance – 20 mg, phenobarbital – 18 mg, peppermint oil – 1.4 mg, hop oil – 0.2 mg;
auxiliary substances: stabilizer, ethanol 96%, purified water.
Medicinal form. Oral drops.
Main physicochemical properties: transparent colorless liquid with a specific smell.
Indication.
– Neuroses with increased irritability;
– insomnia;
– in complex therapy of hypertensive disease and vegetative-vascular dystonia;
– mild spasms of coronary vessels, tachycardia;
– intestinal spasms caused by neurovegetative disorders (as an antispasmodic drug).
Contraindication.
Hypersensitivity to active substances or to any other component of the drug, bromine; acute hepatic porphyria; severe liver and kidney function disorders; diabetes, myasthenia. Medicinal products containing phenobarbital are contraindicated in case of alcoholism, drug and drug addiction (including in the anamnesis); with respiratory diseases with shortness of breath, obstructive syndrome, pronounced arterial hypotension, with acute myocardial infarction; in depression and depressive disorders with the patient’s tendency to suicidal behavior.
Method of application and dosage.
Take 15-30 drops orally before meals with a small amount (30-50 ml) of liquid 2-3 times a day. If necessary, a single dose can be increased to 40-50 drops.
The duration of drug use is determined by the doctor depending on the clinical effect and tolerability of the drug.
Children.
There is no experience of use for the treatment of children, so the drug should not be used in pediatric practice.
Overdose.
Sim p volumes.
Acute (from mild to moderate) poisoning with barbiturates:
dizziness, fatigue, even a deep sleep from which the patient cannot be awakened.
Hypersensitivity reactions may occur: angioedema, urticaria, itching, rash.
Acute severe poisoning:
deep coma accompanied by tissue hypoxia, shallow breathing, first rapid, then slow breathing, rapid heart rate, cardiac arrhythmia, low blood pressure, bradycardia, vascular collapse, weakening or loss of reflexes, nystagmus, headache, nausea, weakness, heart failure , a decrease in body temperature, a slowing of the pulse, a decrease in diuresis.
If poisoning is not treated, death may occur as a result of vascular insufficiency, respiratory paralysis, or pulmonary edema.
Overdose is possible with long-term use of the drug, which is associated with the accumulation of its components. Long-term and constant use can cause addiction, withdrawal syndrome, psychomotor agitation.
Long-term use of products containing bromine can lead to bromine poisoning, characterized by the following symptoms: confusion, ataxia, apathy, depressed mood, conjunctivitis, colds, acne or purpura.
Treatment.
Cases of acute poisoning with Corvaldin® should be treated in the same way as poisoning with other hypnotics and barbiturates, depending on the severity of the symptoms of poisoning. The patient should be transferred to the intensive care unit. Breathing and blood circulation need stability and normalization. Respiratory failure is overcome by performing artificial respiration, shock is stopped by infusion of plasma and plasma substitutes. If a long time has passed since the reception, it is necessary to wash the stomach (inject 10 g of activated carbon powder and sodium sulfate into the stomach). In order to quickly remove barbiturates from the body, it is possible to carry out forced diuresis with alkalis, as well as hemodialysis and/or hemoperfusion.
Treatment of bromine poisoning: the removal of bromine ions from the body can be accelerated by the introduction of a significant amount of table salt solution with the simultaneous introduction of saluretic agents.
In the event of hypersensitivity reactions, prescribe desensitizing drugs.
Expiration date.
3 years.
Do not use the drug after the expiration date indicated on the package.
Storage conditions.
Store in the original packaging at a temperature not higher than 25 °C. Keep out of the reach of children.
Packaging. 25 ml in a bottle. 1 bottle in a pack.
Leave category. Without a prescription.
Producer. “Farmak” JSC.
The location of the manufacturer and its address of the place of business.
Ukraine, 04080, Kyiv, st. Kyrylivska, 74.
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