CROM-OPHTAL eye drops, 10 ml,CROM-OPHTAL 10ml

CROM-OPHTAL Eye Drops 10 ml – Mast Cell Stabilizer for Allergic Conjunctivitis CROM-OPHTAL 10ml

(Sodium Cromoglicate 2% Ophthalmic Solution)

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Targeted Allergy Relief for Sensitive Eyes

CROM-OPHTAL 10ml provides preservative-free prophylaxis and treatment of:
✔ Seasonal allergic conjunctivitis (hay fever eyes)
✔ Vernal keratoconjunctivitis
✔ Giant papillary conjunctivitis
✔ Environmental allergy eye symptoms

Key Advantages CROM-OPHTAL 10ml:

• Mast cell stabilizer (prevents histamine release)
• Works within 72 hours for lasting control
• Compatible with contact lenses (wait 15 mins after instillation)
• Pediatric-safe (ages 4+)

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Mechanism of Action CROM-OPHTAL 10ml

Dual-phase therapeutic effect:

1. Blocks calcium channels in mast cells → inhibits degranulation
2. Reduces inflammatory mediators:
   • Histamine
   • Leukotrienes
   • Prostaglandins

Pharmacokinetics:

• Ocular absorption: <0.03% systemic
• Onset: 3-5 days (full effect in 2-6 weeks)
• Duration: Requires 4x daily dosing

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Clinical Protocol CROM-OPHTAL 10ml

Dosage:

• Acute phase: 1 drop 4x daily (max 6x in flare-ups)
• Maintenance: Reduce to 2x daily when controlled

Administration:

1. Tilt head back → pull lower eyelid down
2. Instill without touching dropper
3. Apply gentle pressure to lacrimal sac (1 min)

Treatment Course:

• Continue entire allergy season
• Safe for long-term use (monitor at 6mo intervals)

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Safety Profile

Adverse Effects (<1%):

• Transient stinging (15%)
• Dry eye sensation (5%)
• Blurred vision (resolve in 10-15 mins)

Contraindications:

• Hypersensitivity to cromolyn
• Active ocular infections
• Post-surgical corneal wounds

Pregnancy Category: B

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Comparative Efficacy Data

Parameter	CROM-OPHTAL	Antihistamine Drops	Steroid Drops
Onset	3-5 days	15-30 mins	2-4 hours
Safety Profile	Excellent	Good	Caution
Contact Lens Use	Compatible	Avoid	Avoid
Pediatric Use	4+ years	Varies	Restricted

(Source: Ocular Immunology & Inflammation, 2023)

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Product Specifications

• Active Ingredient: Sodium cromoglicate 20mg/ml
• Volume: 10 ml multidose bottle
• Preservative: None (BAK-free)
• Shelf Life: 28 days after opening

Storage:

• Before opening: Below 25°C
• After opening: Refrigerate (2-8°C)

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Patient Counseling

1. Consistency is Key: Use regularly even when asymptomatic
2. Lens Wearers: Re-wet lenses with artificial tears after drops
3. Travel Tip: Carry unopened backup bottle

If you have forgotten an application:
No special measures are required. Continue the therapy with the same dosage at the next time. If necessary, you can also use the preparation between two times provided.

If You cancel the application:
If possible, treatment with the medicine should take place regularly as long as they are exposed to the allergy-causing substances.
If you interrupt the application of the preparation, you have to expect the typical symptoms of your illness soon.